Description:
Manipulation under anesthesia (MUA) consists of a series of mobilization, stretching, and traction procedures performed while the patient receives anesthesia (usually general anesthesia or moderate sedation).

Scientific evidence regarding spinal MUA, spinal manipulation with joint anesthesia, and spinal manipulation after epidural anesthesia and corticosteroid injection is limited to observational case series and nonrandomized comparative studies. Evidence regarding the efficacy of MUA over several sessions or for multiple joints is also lacking. Evidence is insufficient to determine whether MUA improves health outcomes; thus, it is considered investigational.

Background
Manipulation is intended to break up fibrous and scar tissue to relieve pain and improve range of motion. Anesthesia or sedation is used to reduce pain, spasm, and reflex muscle guarding that may interfere with the delivery of therapies and to allow the therapist to break up joint and soft tissue adhesions with less force than would be required to overcome patient resistance or apprehension. MUA is generally performed with an anesthesiologist in attendance. MUA is an accepted treatment for isolated joint conditions, such as arthrofibrosis of the knee and adhesive capsulitis. It is also used to treat (reduce) fractures (e.g., vertebral, long bones) and dislocations.

MUA has been proposed as a treatment modality for acute and chronic pain conditions, particularly of the spinal region, when standard care, including manipulation, and other conservative measures have been unsuccessful. MUA of the spine has been used in various forms since the 1930s. Complications from general anesthesia and forceful long-lever, high-amplitude nonspecific manipulation procedures resulted in decreased use of the procedure in favor of other therapies. MUA was modified and revived in the 1990s. This revival is attributed to increased interest in spinal manipulative therapy and the advent of safer, shorter-acting anesthesia agents used for conscious sedation.

MUA of the spine is described as follows: after sedation is achieved, a series of mobilization, stretching, and traction procedures to the spine and lower extremities is performed and may include passive stretching of the gluteal and hamstring muscles with straight-leg raise, hip capsule stretching and mobilization, lumbosacral traction, and stretching of the lateral abdominal and paraspinal muscles. After the stretching and traction procedures, spinal manipulative therapy (SMT) is delivered with high-velocity, short-amplitude thrust applied to a spinous process by hand, while the upper torso and lower extremities are stabilized. SMT may also be applied to the thoracolumbar or cervical area if considered necessary to address the low back pain.

MUA takes 15 to 20 minutes, and after recovery from anesthesia, the patient is discharged with instructions to remain active and use heat or ice for short-term analgesic control. Some practitioners recommend performing the procedure on 3 or more consecutive days for best results. Care after MUA may include 4 to 8 weeks of active rehabilitation with manual therapy, including SMT and other modalities. Manipulation has also been performed after injection of local anesthetic into lumbar zygapophyseal (facet) and/or sacroiliac joints under fluoroscopic guidance (manipulation under joint anesthesia/analgesia) and after epidural injection of corticosteroid and local anesthetic (manipulation postepidural injection). Spinal manipulation under anesthesia has also been combined with other joint manipulation during multiple sessions. Together, these may be referred to as medicine-assisted manipulation.

Policy:
Spinal manipulation under anesthesia (and manipulation of other joints, e.g., hip joint, performed during the procedure) with the patient under anesthesia, spinal manipulation under joint anesthesia, and spinal manipulation after epidural anesthesia and corticosteroid injection areinvestigational and/or unproven and therefore considered NOT MEDICALLY NECESSARY for treatment of chronic spinal (cranial, cervical, thoracic, lumbar) pain and chronic sacroiliac and pelvic pain.

• Spinal manipulation and manipulation of other joints (e.g., hip, ankle, elbow, wrist, and temporomandibular joint) under anesthesia (MUA) involving serial treatment sessions isinvestigational and/or unprovena and therefore considered NOT MEDICALLY NECESSARY  .
• Manipulation under anesthesia involving multiple body joints is investigational and/or unprovena and therefore considered NOT MEDICALLY NECESSARY  for treatment of chronic pain.

Manipulation under anesthesia may be considered MEDICALLY NECESSARY for any of the following isolated joint conditions:

• Adhesive capsulitis (i.e., frozen shoulder) when there is a failure of conservative medical management, including medications with or without articular injections, home exercise programs, and physical therapy (CPT code 23700)
• Arthrofibrosis of the knee following trauma or knee surgery (e.g, total knee replacement, anterior cruciate ligament repair) (CPT code 27570)
• Reduction of a displaced fracture (e.g., vertebral long bones) (e.g, CPT code 22505, 25675)
• Reduction of acute/traumatic dislocation (e.g., vertebral, perched cervical facet) (CPT code 22505)
• Chronic contracture of upper or lower extremity joint (e.g., fixed contracture from a neuromuscular condition) when there is failure of conservative medical management including range of motion exercise programs and physical therapy.

MUA provided for these indications consists of a SINGLE treatment session involving an isolated joint. Serial treatment sessions are not in accordance with generally accepted standards of medical practice and are therefore not medically necessary.

SINGLE or SERIAL treatment sessions of MUA involving any of the following joints or combinations of joints, including multiple body joint MUA, for the management of acute or chronic pain conditions areinvestigational and/or unprovena and therefore considered NOT MEDICALLY NECESSARY. (This list may not be all inclusive): 

• Ankle (CPT code 27860)
• Cervical, thoracic or lumbar spine (e.g., CPT code 22505)
• Elbow (CPT code 24300)
• Finger (e.g., CPT code 26340, 26675)
• Hip (CPT code 27275)
• Pelvis, sacroiliac (CPT code 27194, 27198)
• Temporomandibular (CPT code 21073)
• Thumb (CPT code 26340)
• Toe (CPT code 28665)
• Wrist (CPT code 25259)

Policy Guidelines
Dislocation vs. Subluxation
A distinction must be made between subluxation and dislocation. According to the chiropractic literature a subluxation can be defined as a restriction or loss of normal range of motion of the joint causing dysfunction of the spinal motion segment or peripheral joints. A dislocation can be defined as a disruption in the joint integrity. Typically, a subluxation cannot be detected with imaging studies, while a dislocation can. 

CPT code 22505 specifically identifies manipulation of the spine under anesthesia:

22505: Manipulation of spine requiring anesthesia, any region.

The anesthesia administration for spinal manipulation would be coded using:

00640: Anesthesia for manipulation of the spine or for closed procedures on the cervical, thoracic, or lumbar spine.

Manipulation under anesthesia CPT codes are available for various joints such as 21073 for the temporomandibular joint(s), 23700 for the shoulder, 27275 for the hip joint, 27570 for the knee joint, 27860 for the ankle, etc.

Rationale 
This evidence review was created in May 2002 and has been updated regularly with searches of the PubMed database. The most recent literature update was conducted through February 18, 2022.

Evidence reviews assess the clinical evidence to determine whether the use of a technology improves the net health outcome. Broadly defined, health outcomes are length of life, quality of life, and ability to function including benefits and harms. Every clinical condition has specific outcomes that are important to patients and to managing the course of that condition. Validated outcome measures are necessary to ascertain whether a condition improves or worsens; and whether the magnitude of that change is clinically significant. The net health outcome is a balance of benefits and harms.

To assess whether the evidence is sufficient to draw conclusions about the net health outcome of a technology, 2 domains are examined: the relevance and the quality and credibility. To be relevant, studies must represent 1 or more intended clinical use of the technology in the intended population and compare an effective and appropriate alternative at a comparable intensity. For some conditions, the alternative will be supportive care or surveillance. The quality and credibility of the evidence depend on study design and conduct, minimizing bias and confounding that can generate incorrect findings. The randomized controlled trial (RCT) is preferred to assess efficacy; however, in some circumstances, nonrandomized studies may be adequate. Randomized controlled trials are rarely large enough or long enough to capture less common adverse events and long-term effects. Other types of studies can be used for these purposes and to assess generalizability to broader clinical populations and settings of clinical practice.

Manipulation Under Anesthesia
Clinical Context and Therapy Purpose
The purpose of manipulation under anesthesia is to provide a treatment option that is an alternative to or an improvement on existing therapies, such as conservative management, in patients with chronic spinal, sacroiliac, or pelvic pain.

The question addressed in this evidence review is: Does manipulation under anesthesia improve the net health outcome in individuals with chronic spinal, sacroiliac, or pelvic pain?

The following PICO was used to select literature to inform this review.

Populations
The relevant population of interest is individuals with chronic spinal, sacroiliac, or pelvic pain.

Interventions
The therapy being considered is manipulation under anesthesia.

Manipulation under anesthesia consists of a series of mobilization, stretching, and traction procedures performed while the patient is sedated (usually with general anesthesia or moderate sedation). Manipulation under anesthesia takes 15 to 20 minutes, and after recovery from anesthesia the patient is discharged with instructions to remain active and use heat or ice for short-term analgesic control.

Comparators
Comparators of interest include conservative management.

Conservative management includes steroid regimens, blood pressure medication, muscle relaxers, and physical therapy.

Outcomes
The general outcomes of interest are symptoms, functional outcomes, quality of life, and treatment-related morbidity.

The existing literature evaluating manipulation under anesthesia as a treatment for chronic spinal, sacroiliac, or pelvic pain has varying lengths of follow-up, ranging from 2 weeks to 6 months. While studies described below all reported at least 1 outcome of interest, longer follow-up was necessary to fully observe outcomes. Therefore, 6 months of follow-up is considered necessary to demonstrate efficacy.

Table 1 summarizes the patient-reported outcome measures described in this review.

Table 1. Patient Self-Administered Outcome Measure Tools

Name	Description	Scoring	MCID
Numeric Pain Scale1	Numbered scale by which patients rate their pain, similar to VAS	0 – 10 scale: 10 = excruciating pain 0 = no pain	Reduction of ≥ 2 points (≈ 30%) to be clinically important
Roland-Morris Disability Questionnaire2	24 questions that measure low back pain-related disability	“Yes” answers are totaled to determine disability (1 to 24) Score of ≥ 14 represents significant disability	Change of ≥ 4 points required for clinically applicable change to be measured accurately
Bournemouth Questionnaire3	7-question, multidimensional tool to assess outcome of care in a routine clinical setting Takes into account cognitive and affective aspects of pain Two versions: low back pain and nonspecific neck pain	Each question rated on a numeric rating scale from 0 to 10: 0 = much better 5 = no change 10 = much worse Scores are totaled, for minimum of 0 and maximum of 70	Percentage improvement of 47% in back pain and 34% in neck pain
Patient’s Global Impression of Change3	7-point scale of how a patient perceives the efficacy of treatment, a rating of overall improvement from baseline	Scale of 1 to 7: 1 = no change or condition is worse 2 = almost the same 3 = a little better, but no noticeable change 4 = somewhat better, but no real difference 5 = moderately better, slight noticeable change 6 = better, definite improvement with real difference 7 = a great deal better, considerable improvement	Clinically relevant improvement, response of ± 6

MCID: minimal clinically important difference; VAS: visual analog scale.

Study Selection Criteria
Methodologically credible studies were selected using the following principles:

• To assess efficacy outcomes, comparative controlled prospective trials were sought, with a preference for RCTs.
• In the absence of such trials, comparative observational studies were sought, with a preference for prospective studies.
• To assess long-term outcomes and adverse events, single-arm studies that capture longer periods of follow-up and/or larger populations were sought.
• Studies with duplicative or overlapping populations were excluded.

Review of Evidence
Dagenais et al. (2008) conducted a comprehensive review of the history of manipulation under anesthesia or medicine-assisted manipulation and the published experimental literature.⁴ The authors noted there was no research to confirm theories about a mechanism of action for these procedures and that the only RCT identified was published in 1971 when the techniques for spinal manipulation differed from those used presently.

Nonrandomized Comparative Studies
No high-quality RCTs have been identified. A comprehensive review of the literature by Digiorgi (2013)⁵ described studies by Kohlbeck et al (2005)⁶ and Palmieri and Smoyak (2002)² as being the best evidence available for medicine-assisted manipulation and manipulation under anesthesia of the spine.

Kohlbeck et al. (2005) reported on a nonrandomized comparative study that included 68 patients with chronic low back pain.⁶ All patients received an initial 4- to 6-week trial of spinal manipulation therapy, after which 42 patients received supplemental intervention with manipulation under anesthesia and 26 continued with spinal manipulative therapy. Low back pain and disability measures favored the manipulation under anesthesia group over the spinal manipulative therapy only group at 3 months (adjusted mean difference on a 100-point scale, 4.4 points; 95% confidence interval [CI], -2.2 to 11.0). This difference attenuated at 1 year (adjusted mean difference, 0.3 points; 95% CI, -8.6 to 9.2). The relative odds of experiencing a 10-point improvement in pain and disability favored the manipulation under anesthesia group at 3 months (odds ratio (OR), 4.1; 95% CI, 1.3 to 13.6) and 1 year (OR, 1.9; 95% CI, 0.6 to 6.5).

Palmieri and Smoyak (2002) evaluated the efficacy of self-reported questionnaires to study manipulation under anesthesia in a convenience sample of 87 subjects from 2 ambulatory surgery centers and 2 chiropractic clinics.² Thirty-eight patients with low back pain received manipulation under anesthesia and 49 received traditional chiropractic treatment. A numeric rating scale for pain and the Roland-Morris Disability Questionnaire were administered at baseline, after the procedure, and 4 weeks later. Average pain scale scores in the manipulation under anesthesia group decreased by 50% and by 26% in the traditional treatment group; Roland-Morris Disability Questionnaire scores decreased by 51% and 38%, respectively. Although the authors concluded that the study supported the need for large-scale studies on manipulation under anesthesia and that the assessments were easily administered and dependable, no large-scale studies comparing manipulation under anesthesia with traditional chiropractic treatment have been identified.

Observational Studies
Peterson et al. (2014) reported on a prospective study of 30 patients with chronic pain (17 lower back, 13 neck) who underwent a single manipulation under anesthesia session with follow-up at 2 and 4 weeks.⁷ The primary outcome measure was the Patient’s Global Impression of Change. At 2 weeks, 52% of the patients reported clinically relevant improvement (better or much better), with 45.5% improved at 4 weeks. There was a statistically significant reduction in numeric rating scale scores for pain at 4 weeks (p = .01), from a mean baseline score of 4.0 to 3.5 at 2 weeks post-manipulation under anesthesia. Bournemouth Questionnaire scores improved from 24.17 to 20.38 at 2 weeks (p = 0.008) and 19.45 at 4 weeks (p = .001). This study lacked a sham group to control for a potential placebo effect. Also, the clinical significance of improved numeric rating scale and Bournemouth Questionnaire scores is unclear, although Hurst and Bolton (2004) described the Bournemouth Questionnaire as a percentage improvement of 47% in back pain and 34% in neck pain.³

West et al. (1999) reported on a series of 177 patients with pain arising from the cranial, cervical, thoracic, and lumbar spine, as well as the sacroiliac and pelvic regions, who had failed conservative and surgical treatment.⁸ Patients underwent 3 sequential manipulations with intravenous sedation followed by 4 to 6 weeks of spinal manipulation and therapeutic modalities; all had 6 months of follow-up. On average, visual analog scale scores improved by 62% in patients with cervical pain and by 60% in patients with lumbar pain. Dougherty et al. (2004) retrospectively reviewed outcomes of 20 cervical and 60 lumbar radiculopathy patients who underwent spinal manipulation after epidural injection.⁹ After epidural injection of lidocaine (guided fluoroscopically or with computed tomography), methylprednisolone acetate flexion distraction mobilization and then high-velocity, low-amplitude spinal manipulation were delivered to the affected spinal regions. Outcome criteria were empirically defined as a significant improvement, temporary improvement, or no change. Among lumbar spine patients, 22 (37%) noted significant improvement, 25 (42%) reported temporary improvement, and 13 (22%) no change. Among patients receiving a cervical epidural injection, 10 (50%) had significant improvement, 6 (30%) had temporary relief, and 4 (20%) had no change.

The only study on manipulation under joint anesthesia or analgesia evaluated 4 subjects; it was reported by Dreyfuss et al. (1995).¹⁰ Later, Michaelsen (2000) noted that joint-related manipulation under anesthesia should be viewed with “guarded optimism because its success is based solely on anecdotal experience.”¹¹

Table 2. Summary of Characteristics of Key Observational Studies of Manipulation Under Anesthesia

Study	Study Type	Country	Dates	Participants	Treatment	Follow-Up
Peterson (2014)7	Prospective	Switzerland	NR	Patients (N=30) with chronic pain who underwent a single MUA session	MUA for those with low back pain (n = 17); MUA for those with neck pain (n = 13)	2 and 4 weeks
West (1999)8	Case series	U.S.	July 1995 – Feb 1997	177 patients with pain arising from the cranial, cervical, thoracic, and lumbar spine, as well as the sacroiliac and pelvic regions who had failed conservative and surgical treatment	Patients underwent 3 sequential manipulations with intravenous sedation followed by 4 to 6 weeks of spinal manipulation and therapeutic modalities	6 months
Dougherty (2004)9	Retrospective	U.S.	Nov 1996 – Nov 2000	20 cervical and 60 lumbar radiculopathy patients who underwent spinal manipulation after epidural injection. The patients ranged in age from 21-76 years with an average age of 43 years. Forty-three percent of the patients were female and 57% were male.	Following epidural injection of lidocaine (guided fluoroscopically or with computed tomography), methylprednisolone acetate flexion distraction mobilization and high-velocity, low-amplitude spinal manipulation were delivered to the affected spinal regions	1 year

MUA: manipulation under anesthesia; NR: not reported.

Table 3. Summary of Results of Key Observational Studies of Manipulation Under Anesthesia

Study	Improvement as Reported by Participant	Bournemouth Questionnaire Scores	Patient’s Global Impression of Change
Peterson (2014)7
Baseline		24.17
2 weeks post		20.38 (p = .008)
4 weeks post		19.45 (p = .001)
“better or much better” reported at 2 weeks post			52%
“better or much better” reported at 4 weeks post			45.5%
West (1999)8
% of cervical patients with improvement			62%
% of lumbar patients with improvement			60%
Dougherty (2004)9
Lumbar spine patients
% noting significant improvement	22 (37%)
% noting temporary improvement	25 (42%)
% noting no improvement	13 (22%)
Patients receiving cervical epidural injection
% noting significant improvement	10 (50%)
% noting temporary improvement	6 (30%)
% noting no improvement	4 (20%)

Summary of Evidence
For individuals who have chronic spinal, sacroiliac, or pelvic pain who receive manipulation under anesthesia, the evidence includes case series, observational studies, and nonrandomized comparative studies. Relevant outcomes are symptoms, functional outcomes, quality of life, and treatment-related morbidity. Scientific evidence on spinal manipulation under anesthesia, spinal manipulation with joint anesthesia, and spinal manipulation after epidural anesthesia and corticosteroid injection is very limited. No RCTs have been identified. Evidence on the efficacy of manipulation under anesthesia over several sessions or for multiple joints is also lacking. The evidence is insufficient to determine that the technology results in an improvement in the net health outcome.

The purpose of the following information is to provide reference material. Inclusion does not imply endorsement or alignment with the evidence review conclusions.

Clinical Input From Physician Specialty Societies and Academic Medical Centers
While the various physician specialty societies and academic medical centers may collaborate with and make recommendations during this process, through the provision of appropriate reviewers, input received does not represent an endorsement or position statement by the physician specialty societies or academic medical centers, unless otherwise noted.

2009 Input
Clinical input was sought to help determine whether the use of manipulation under anesthesia for individuals with chronic spinal and pelvic pain would provide a clinically meaningful improvement in net health outcome and whether the use is consistent with generally accepted medical practice. In response to requests, input was received from 2 physician specialty societies and 4 academic medical centers while this policy was under review. Input from the 7 reviewers agreed that manipulation under anesthesia for chronic spinal and pelvic pain is investigational.

Practice Guidelines and Position Statements
Guidelines or position statements will be considered for inclusion in ‘Supplemental Information' if they were issued by, or jointly by, a U.S. professional society, an international society with U.S. representation, or National Institute for Health and Care Excellence (NICE). Priority will be given to guidelines that are informed by a systematic review, include strength of evidence ratings, and include a description of management of conflict of interest.

American Association of Manipulation Under Anesthesia Providers
In 2014, The American Association of Manipulation Under Anesthesia Providers published consensus-based guidelines for the practice and performance of manipulation under anesthesia.¹² The guidelines included patient selection criteria (see below), establishing medical necessity, frequency and follow-up procedures, parameters for determining manipulation under anesthesia progress, general post-manipulation under anesthesia therapy, and safety. The guidelines recommended 3 consecutive days of treatment, based on the premise that serial procedures allow a gentler yet effective treatment plan with better control of biomechanical force. The guidelines also recommended follow-up therapy without anesthesia over 8 weeks after manipulation under anesthesia that included all fibrosis release and manipulative procedures performed during the manipulation under anesthesia procedure to help prevent re-adhesion.

Patient selection criteria include, but are not limited to, the following:

• "The patient has undergone an adequate trial of appropriate care ... and continues to experience intractable pain, interference to activities of daily living, and/or biomechanical dysfunction.
• "Sufficient care has been rendered prior to recommending manipulation under anesthesia. A sufficient time period is usually considered a minimum of 4 to 8 weeks, but exceptions may apply depending on the patient's individual needs....
• "Physical medicine procedures have been utilized in a clinical setting during the 6 to 8 week period prior to recommending manipulation under anesthesia.
• "Diagnosed conditions must fall within the recognized categories of conditions responsive to manipulation under anesthesia. The following disorders are classified as acceptable conditions for utilization of manipulation under anesthesia:
  1. "Patients for whom manipulation of the spine or other articulations is the treatment of choice; however, the patient's pain threshold inhibits the effectiveness of conservative manipulation.
  2. "Patients for whom manipulation of the spine or other articulations is the treatment of choice; however, due to the extent of the injury mechanism, conservative manipulation has been minimally effective . ..and a greater degree of movement of the affected joint(s) is needed to obtain patient progress.
  3. "Patients for whom manipulation of the spine or other articulations is the treatment of choice by the doctor; however due to the chronicity of the problem, and/or the fibrous tissue adhesions present, in-office manipulation has been incomplete and the plateau in the patient's improvement is unsatisfactory.
  4. "When the patient is considered for surgical intervention, manipulation under anesthesia is an alternative and/or an interim treatment and may be used as a therapeutic and/or diagnostic tool in the overall consideration of the patient's condition.
  5. "When there are no better treatment options available for the patient in the opinions of the treating doctor and patient."¹²

U.S. Preventive Services Task Force Recommendations
Not applicable

Ongoing and Unpublished Clinical Trials
There were no ongoing or unpublished trials regarding this policy as of February 2022.

References:

1. Farrar JT, Young JP, LaMoreaux L, et al. Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale. Pain. Nov 2001; 94(2): 149-158. PMID 11690728
2. Palmieri NF, Smoyak S. Chronic low back pain: a study of the effects of manipulation under anesthesia. J Manipulative Physiol Ther. Oct 2002; 25(8): E8-E17. PMID 12381983
3. Hurst H, Bolton J. Assessing the clinical significance of change scores recorded on subjective outcome measures. J Manipulative Physiol Ther. Jan 2004; 27(1): 26-35. PMID 14739871
4. Dagenais S, Mayer J, Wooley JR, et al. Evidence-informed management of chronic low back pain with medicine-assisted manipulation. Spine J. Jan-Feb 2008; 8(1): 142-9. PMID 18164462
5. Digiorgi D. Spinal manipulation under anesthesia: a narrative review of the literature and commentary. Chiropr Man Therap. May 14 2013; 21(1): 14. PMID 23672974
6. Kohlbeck FJ, Haldeman S, Hurwitz EL, et al. Supplemental care with medication-assisted manipulation versus spinal manipulation therapy alone for patients with chronic low back pain. J Manipulative Physiol Ther. May 2005; 28(4): 245-52. PMID 15883577
7. Peterson CK, Humphreys BK, Vollenweider R, et al. Outcomes for chronic neck and low back pain patients after manipulation under anesthesia: a prospective cohort study. J Manipulative Physiol Ther. Jul-Aug 2014; 37(6): 377-82. PMID 24998720
8. West DT, Mathews RS, Miller MR, et al. Effective management of spinal pain in one hundred seventy-seven patients evaluated for manipulation under anesthesia. J Manipulative Physiol Ther. Jun 1999; 22(5): 299-308. PMID 10395432
9. Dougherty P, Bajwa S, Burke J, et al. Spinal manipulation postepidural injection for lumbar and cervical radiculopathy: a retrospective case series. J Manipulative Physiol Ther. Sep 2004; 27(7): 449-56. PMID 15389176
10. Dreyfuss P, Michaelsen M, Horne M. MUJA: manipulation under joint anesthesia/analgesia: a treatment approach for recalcitrant low back pain of synovial joint origin. J Manipulative Physiol Ther. Oct 1995; 18(8): 537-46. PMID 8583177
11. Michaelsen MR. Manipulation under joint anesthesia/analgesia: a proposed interdisciplinary treatment approach for recalcitrant spinal axis pain of synovial joint origin. J Manipulative Physiol Ther. Feb 2000; 23(2): 127-9. PMID 10714542
12. Gordon R, Cremata E, Hawk C. Guidelines for the practice and performance of manipulation under anesthesia. Chiropr Man Therap. Feb 03 2014; 22(1): 7. PMID 24490957 

Coding Section

Codes	Number	Description
CPT		See Policy Guidelines
	27198 (effective 1/1/2017)	Closed treatment of posterior pelvic ring fracture(s), dislocation(s), diastasis or subluxation of the ilium, sacroiliac joint, and/or sacrum, with or without anterior pelvic ring fracture(s) and/or dislocation(s) of the pubic symphysis and/or superior/inferior rami, unilateral or bilateral; with manipulation, requiring more than local anesthesia (ie, general anesthesia, moderate sedation, spinal/epidural)
ICD-9 Diagnosis		Investigational for all diagnoses
ICD-10-CM (effective 10/01/15)		Investigational for all relevant diagnoses
	M47.011-M47.9	Spondylosis code range
	M54.00-M54.9	Dorsalgia code range
ICD-10-PCS (effective 10/01/15)		ICD-10-PCS codes are only used for inpatient services.
	ORN0XZZ, ORN1XZZ, ORN3XZZ, ORN4XZZ, ORN5XZZ, ORN6XZZ, ORN9XZZ, ORNAXZZ, ORNBXZZ	Surgical, upper joints, release, external, codes by anatomical location
	OSN0XZZ, OSN2XZZ, OSN3XZZ, OSN4XZZ, OSN5XZZ, OSN6XZZ	Surgical, lower joints, release, external, codes by anatomical location
Type of Service
Place of Service

Procedure and diagnosis codes on Medical Policy documents are included only as a general reference tool for each policy. They may not be all-inclusive.

This medical policy was developed through consideration of peer-reviewed medical literature generally recognized by the relevant medical community, U.S. FDA approval status, nationally accepted standards of medical practice and accepted standards of medical practice in this community, Blue Cross Blue Shield Association technology assessment program (TEC) and other nonaffiliated technology evaluation centers, reference to federal regulations, other plan medical policies, and accredited national guidelines.

"Current Procedural Terminology © American Medical Association. All Rights Reserved" 

History From 2014 Forward     

05/03/2023	Annual review, no change to policy intent
05/05/2022	Annual review, no change to policy intent. Updating rationale and references.
05/04/2021	Annual review, no change to policy intent.
05/11/2020	Annual review, no change to policy intent. Updating rationale and references.
05/01/2019	Annual review, no change to policy intent.
05/17/2018	Annual review, no change to policy intent. Updating rationale.
05/18/2017	Annual review, no change to policy intent. Updating rationale and references.
11/22/2016	Updated Coding section and policy section with code 27198 code for 2017.
05/04/2016	Annual review, no change to policy intent.
05/05/2015	Annual review, no change to policy intent. Updated rationale, references, background, description and guidelines. Added coding.
05/08/2014	Annual review. Updated rationale and references. No change to policy intent.