Dynamic Spinal Visualization and Vertebral Motion Analysis - CAM 60146HB

Description:
Dynamic spinal visualization is a general term addressing different imaging technologies that simultaneously visualize spine (vertebrae) movements and external body movement. Vertebral motion analysis uses similar imaging as dynamic spinal visualization, with the addition of controlled movement and computerized tracking. These technologies have been proposed for the evaluation of spinal disorders including neck and back pain. 

For individuals who have neck or back pain who receive dynamic spinal visualization, the evidence includes comparative trials. Relevant outcomes are test accuracy, symptoms, and functional outcomes. Techniques include digital motion X-rays, cineradiography/videofluoroscopy, or dynamic magnetic resonance imaging of the spine and neck. The available studies compare spine kinetics in patients who had neck or back pain with that in healthy controls. No literature was identified on the diagnostic accuracy of dynamic visualization in a relevant patient population. No evidence was identified on the effect of this technology on symptoms or functional outcomes. The evidence is insufficient to determine the effects of the technology on health outcomes. 

For individuals who have back or neck pain who receive vertebral motion analysis, the evidence includes comparisons to standard flexion/extension radiographs. Relevant outcomes are test accuracy, symptoms, and functional outcomes. These studies reported that vertebral motion analysis reduces variability in measurement of rotational and translational spine movement compared with standard flexion/extension radiographs. Whether the reduction in variability improves diagnostic accuracy or health outcomes is uncertain. The single study that reported on diagnostic accuracy lacked a true criterion standard, limiting interpretation of findings. The evidence is insufficient to determine the effects of the technology on health outcomes.

Background 
Flexion/Extension Radiography
Dynamic spinal visualization and vertebral motion analysis are proposed for individuals who are being evaluated for back or neck pain and are being considered for standard flexion/extension radiographs. Flexion/extension radiographs may be performed with a passive external force or by the patient's own movement. Typically, radiographs are taken at the end ranges of flexion and extension and the intervertebral movements (rotation and translation) are measured to assess spinal instability. Flexion/extension radiographs may be used to assess radiographic instability in order to diagnose and determine the most effective treatment (e.g., physical therapy, decompression, or spinal fusion) or to assess the efficacy of spinal fusion.

Dynamic Spinal Visualization
Digital Motion X-Ray
Most spinal visualization technologies use X-rays to create images either on film, video monitor, or computer screen. Digital motion X-ray involves the use of film X-ray or computer-based X-ray "snapshots" taken in sequence as a patient moves. Film X-rays are digitized into a computer for manipulation, while computer-based X-rays are automatically created in a digital format. Using a computer program, the digitized snapshots are then sequenced and played on a video monitor, creating a moving image of the inside of the body. This moving image can then be evaluated by a physician alone or by using computer software that evaluates several aspects of the body's structure, such as intervertebral flexion and extension, to determine the presence or absence of abnormalities.

Videofluoroscopy and Cineradiography
Videofluoroscopy and cineradiography are different names for the same procedure, which uses fluoroscopy to create real-time video images of internal structures of the body. Unlike standard X-rays, which take a single picture at one point in time, fluoroscopy provides motion pictures of the body. The results of these techniques can be displayed on a video monitor as the procedure is being conducted, as well as recorded, to allow computer analysis or evaluation at a later time. Like digital motion X-ray, the results can be evaluated by a physician alone or with the assistance of computer software.

Dynamic Magnetic Resonance Imaging (MRI)
Dynamic MRI is also being developed to image the cervical spine. This technique uses an MRI-compatible stepless motorized positioning device and a real-time true fast imaging with steady-state precession sequence to provide passive kinematic imaging of the cervical spine. The quality of the images is lower than a typical MRI sequence but is proposed to be adequate to observe changes in the alignment of vertebral bodies, the width of the spinal canal, and the spinal cord. Higher-resolution imaging can be performed at the end positions of flexion and extension.

Vertebral Motion Analysis
Vertebral motion analysis systems like the KineGraph VMA (Vertebral Motion Analyzer) provide assisted bending with fluoroscopic imaging and computerized analysis. The device uses facial recognition software to track vertebral bodies across the images. Proposed benefits of the vertebral motion analysis are a reduction in patient-driven variability in bending and assessment of vertebral movement across the entire series of imaging rather than at the end range of flexion and extension.

Regulatory Status
In 2012, the KineGraph VMA™ (Vertebral Motion Analyzer; Ortho Kinematics) was cleared for marketing by the U.S. Food and Drug Administration (FDA) through the 510(k) process (k133875). The system includes a Motion Normalizer™ for patient positioning, standard fluoroscopic imaging, and automated image recognition software. Processing of scans by Ortho Kinematics is charged separately. Table 1 lists a sampling of the spinal visualization and motion analysis devices currently cleared by the FDA. FDA product code: LLZ.

Table 1. Spinal Visualization and Motion Analysis Devices Cleared by the U.S. Food and Drug Administration

Device Manufacturer Date Cleared 510(k) No. Indication
SuRgical Planner (SRP) BrainStorm Surgical Theater, Inc. 07/17/2020 K201465 For use in spinal visualization and motion analysis for neck and back pain
Bone VCAR (BVCAR) GE Medical Systems SCS 4/8/2019 K183204 For use in spinal visualization and motion analysis for neck and back pain
Visualase Thermal Therapy System Medtronic Navigation Inc. 3/6/2019 K181859 For use in spinal visualization and motion analysis for neck and back pain
mediCAD 4.0 mediCAD Hectec Gmbh 9/7/2018 K170702 For use in spinal visualization and motion analysis for neck and back pain
VirtuOst Vertebral Fracture Assessment O.N. Diagnostics LLC. 8/3/2018 K171435 For use in spinal visualization and motion analysis for neck and back pain
SPIN-SWI SpinTech Inc. 2/23/2018 K173224 For use in spinal visualization and motion analysis for neck and back pain
X-PSI Knee System Orthosoft Inc. (d/b/a Zimmer CAS) 12/28/2017 K171269 For use in spinal visualization and motion analysis for neck and back pain
Surgical Planning Software Version 1.1 Ortho Kinematics Inc. 11/8/2017 K173247 For use in spinal visualization and motion analysis for neck and back pain
OrthoVision Ewoo Soft Co. Ltd. 10/26/2017 K173094 For use in spinal visualization and motion analysis for neck and back pain
VMAâ„¢ System version 3.0 Ortho Kinematics Inc. 8/25/2017 K172327 For use in spinal visualization and motion analysis for neck and back pain
OKI Surgical Planning Software Ortho Kinematics Inc. 8/22/2017 K171617 For use in spinal visualization and motion analysis for neck and back pain
UNiD Spine Analyzer MEDICREA INTERNATIONAL 5/24/2017 K170172 For use in spinal visualization and motion analysis for neck and back pain
Dynamika IMAGE ANALYSIS LIMITED 5/17/2017 K161601 For use in spinal visualization and motion analysis for neck and back pain
QuantX Quantitative Insights Inc. 5/17/2017 K170195 For use in spinal visualization and motion analysis for neck and back pain
Move Forward 3D Motion Simulation Service BIOMET INC. 3/31/2017 K162559 For use in spinal visualization and motion analysis for neck and back pain
kneeEOS ONEFIT Medical 10/3/2016 K161828 For use in spinal visualization and motion analysis for neck and back pain
JointPoint JOINTPOINT INC. 8/3/2016 K160284 For use in spinal visualization and motion analysis for neck and back pain
EndoSize Therenva SAS 4/12/2016 K160376 For use in spinal visualization and motion analysis for neck and back pain
spineEOS ONEFIT MEDICAL 4/8/2016 K160407 For use in spinal visualization and motion analysis for neck and back pain
Philips Eleva Workspot with SkyFlow Philips Medical Systems DMC GmbH 12/22/2015 K153318 For use in spinal visualization and motion analysis for neck and back pain
OrthoVis Web Portal CUSTOM ORTHOPAEDIC SOLUTIONSINC. 10/2/2015 K151501 For use in spinal visualization and motion analysis for neck and back pain
Arthrex OrthoVis Preoperative Plan Custom Orthopaedic Solutions Inc. 7/31/2015 K151568 For use in spinal visualization and motion analysis for neck and back pain
Centricity Universal Viewer GE HEALTHCARE 5/26/2015 K150420 For use in spinal visualization and motion analysis for neck and back pain
SPINEDESIGN Spine Surgery Planning (Software Application) MEDTRONIC SOFAMOR DANEK USA INC. 5/22/2015 K142648 For use in spinal visualization and motion analysis for neck and back pain

Policy:
The use of dynamic spinal visualization is investigational and/or unproven and therefore considered NOT MEDICALLY NECESSARY.

Vertebral motion analysis is investigational and/or unproven and is therefore considered NOT MEDICALLY NECESSARY. 

Policy Guidelines
Cineradiography/videofluoroscopy can be used once per anatomic area with modifier -59 (distinct procedural service) appended to the code when it is used for additional anatomic regions.

These procedures have both a technical and a professional component. 

There is no specific code for vertebral motion analysis and some dynamic spinal visualization techniques. In such circumstances, refer to the unlisted codes in the codes table. 

Benefit Application
BlueCard/National Account Issues
State or federal mandates (e.g., FEP) may dictate that all devices approved by the U.S. Food and Drug Administration (FDA) may not be considered investigational and, thus, these devices may be assessed only on the basis of their medical necessity.

Rationale 
Evidence reviews assess whether a medical test is clinically useful. A useful test provides information to make a clinical management decision that improves the net health outcome. That is, the balance of benefits and harms is better when the test is used to manage the condition than when another test or no test is used to manage the condition.

The first step in assessing a medical test is to formulate the clinical context and purpose of the test. The test must be technically reliable, clinically valid, and clinically useful for that purpose. Evidence reviews assess the evidence on whether a test is clinically valid and clinically useful. Technical reliability is outside the scope of these reviews, and credible information on technical reliability is available from other sources.

Dynamic Spinal Visualization
Clinical Context and Test Purpose

The purpose of dynamic spinal visualization in patients who have neck or back pain is to determine whether the abnormal movement of the spine contributes to neck or back pain. This would inform clinical decision making about the appropriate intervention, either physical therapy or surgery.

The question addressed in this evidence review is: Does the use of dynamic spinal visualization provide additional information beyond that obtained with conventional imaging technology and does this additional information improve the net health outcome?

The following PICO was used to select literature to inform this review.

Populations
The relevant population of interest is individuals with back or neck pain.

Interventions
The test being considered is dynamic spinal visualization.

Comparators
The following tests are currently being used to make decisions about managing abnormal movement contributing to back and neck pain: conventional radiography and magnetic resonance imaging (MRI).

Outcomes
The general outcomes of interest are test accuracy, symptoms, and functional outcomes. Specific outcomes of interest are whether dynamic spinal visualization leads to new findings and whether these findings improve health outcomes, including pain and function. Timing of short-term outcomes is after completion of physical therapy or surgery.

Study Selection Criteria
For the evaluation of the clinical utility of dynamic spinal visualization, studies would need to use the technology as either an adjunct or a replacement to current tests being used to make decisions about managing abnormal movement in patients with neck and back pain. Outcomes would be symptoms and functional outcomes.

In the absence of direct evidence for the clinical utility of dynamic spinal visualization, evidence for clinical validity is evaluated, with which we can make inferences on clinical utility. Below are selection criteria for studies to assess clinical validity:

  • The study population represents the population of interest; eligibility and selection are described.
  • The test is compared with a credible reference standard.
  • If the test is intended to replace or be an adjunct to an existing test, it should also be compared with that test.
  • Studies should report sensitivity, specificity, and predictive values. Studies that completely report true- and false-positive results are ideal. Studies reporting other measures (eg, receiver operating characteristics [ROC], area under ROC curve [AUROC], c-statistic, likelihood ratios) may be included but are less informative.

Clinically Valid
A test must detect the presence or absence of a condition, the risk of developing a condition in the future, or treatment response (beneficial or adverse).

Review of Evidence
As of the most recent literature update, the evidence on dynamic spinal visualization remains predominantly comparisons of spine kinetics in patients with neck or back pain to healthy controls.

Systematic Reviews
A systematic review by Xu et al. (2017) reviewed 13 studies on dynamic supine MRI for patients with cervical spondylotic myelopathy, although it appears that the studies evaluated flexion/extension images rather than continuous motion.1

Case-Control Studies
Teyhen et al. (2007) compared 20 patients with lower back pain to 20 healthy controls to provide construct validity for a clinical prediction rule that would identify patients likely to benefit from stabilization exercises,2 while Ahmadi et al. (2009) used digital videofluoroscopy to compare 15 patients who had lower back pain with 15 controls to refine criteria for diagnosing lumbar segmental instability.3,

Retrospective Studies
Walter et al. (2021) conducted a feasibility study in 21 patients to assess the diagnostic accuracy and sensitivity of 3 different dynamic MRI protocols for diagnosing spondylolisthesis in the cervical or lumbar spine, using flexion-extension radiographs as the reference standard.4 The 3 dynamic MRI protocols examined were Half-Fourier acquisition single-shot turbo spin-echo imaging (HASTE), continuous real-time radial gradient-echo (GRE), and true fast imaging with steady state precession (True FISP). In this study, overall diagnostic accuracy was 92.9%, 90.5%, and 92.9% with HASTE, GRE, and True FISP, respectively. Overall sensitivity for detecting spondylolisthesis was 68.8%, 68.8%, and 78.6%, respectively.

Clinically Useful
A test is clinically useful if the use of the results informs management decisions that improve the net health outcome of care. The net health outcome can be improved if patients receive correct therapy, more effective therapy, or avoid unnecessary therapy or testing.

Review of Evidence
Direct Evidence

Direct evidence of clinical utility is provided by studies that have compared health outcomes for patients managed with and without the test. Because these are intervention studies, the preferred evidence would be from randomized controlled trials (RCTs).

No RCTs were identified that support the clinical utility of dynamic spinal visualization for this population.

The literature evaluating the clinical utility of dynamic spinal visualization techniques, including digital motion X-ray and cineradiography (videofluoroscopy) for the evaluation and assessment of the spine, is limited to a few studies involving small numbers of participants.5,6,7 No evidence was identified to indicate that clinical use improves health outcomes.

Chain of Evidence
Indirect evidence on clinical utility rests on clinical validity. If the evidence is insufficient to demonstrate test performance, no inferences can be made about clinical utility.

Because the clinical validity of dynamic spinal visualization has not been established, a chain of evidence cannot be constructed.

Section Summary: Dynamic Spinal Visualization
The literature evaluating the clinical utility of dynamic spinal visualization techniques, including digital motion X-ray and cineradiography (videofluoroscopy) and dynamic MRI, for the evaluation and assessment of the spine, is limited to a few studies involving small numbers of participants. Most available studies have compared spine kinetics in patients who had neck or back pain with spine kinetics in healthy controls. In a feasibility study of 21 patients examining dynamic MRI for the detection of spondylolisthesis, 3 dynamic MRI protocols demonstrated sensitivities of 68.8% to 78.6% when compared to standard flexion-extension radiographs. No evidence was identified to indicate that clinical use improves health outcomes such as symptoms or function.

Vertebral Motion Analysis
Clinical Context and Test Purpose

The purpose of vertebral motion analysis in patients with neck or back pain is to determine whether the abnormal movement of the spine contributes to neck or back pain. This would inform clinical decision making about the appropriate intervention, either physical therapy or surgery. Vertebral motion analysis might also be used to assess the success of fusion.

The question addressed in this evidence review is: Does the use of vertebral motion analysis provide additional information beyond that obtained with conventional imaging technology and does this additional information improve the net health outcome?

The following PICO was used to select literature to inform this review.

Populations
The relevant population of interest is individuals with back or neck pain who are being considered for standard flexion/extension radiographs.

Interventions
The test being considered is vertebral motion analysis.

Comparators
The following tests are currently being used to make decisions about managing abnormal movement contributing to back and neck pain: conventional radiography and MRI.

Outcomes
The general outcomes of interest are test accuracy, symptoms, and functional outcomes. The specific outcomes of interest are whether vertebral motion analysis leads to new findings and whether these findings improve health outcomes, including pain and function. Timing of short-term outcomes is after completion of physical therapy or surgery.

Study Selection Criteria
For the evaluation of the clinical utility of vertebral motion analysis, studies would need to use the technology as either an adjunct or a replacement to current tests being used to make decisions about managing abnormal movement in patients with neck and back pain. Outcomes would be symptoms and functional outcomes.

In the absence of direct evidence for the clinical utility of vertebral motion analysis, evidence for clinical validity is evaluated, with which we can make inferences on clinical utility. Below are selection criteria for studies to assess clinical validity:

  • The study population represents the population of interest; eligibility and selection are described.
  • The test is compared with a credible reference standard.
  • If the test is intended to replace or be an adjunct to an existing test, it should also be compared with that test.
  • Studies should report sensitivity, specificity, and predictive values. Studies that completely report true- and false-positive results are ideal. Studies reporting other measures (e.g., ROC, AUROC, c-statistic, likelihood ratios) may be included but are less informative.

Clinically Valid
A test must detect the presence or absence of a condition, the risk of developing a condition in the future, or treatment response (beneficial or adverse).

Review of Evidence
Cheng et al. (2016) and Yeager et al. (2014) reported that vertebral motion analysis decreased variability in the measurement of lumbar spinal movement compared with a digitized manual technique.8,9 Diagnostic performance of vertebral motion analysis was reported by Davis et al. (2015) in a retrospective study of 509 symptomatic patients and 73 asymptomatic participants.10 The comparator was rotational and translational movement from flexion/extension radiographs. The investigators considered instability in symptomatic patients to be true-positive and instability in asymptomatic participants as false-positive, leading to reported differences in diagnostic accuracy between standard flexion/extension radiographs and vertebral motion analysis. In the absence of a true reference standard, the interpretation of this study is limited.

Clinically Useful
A test is clinically useful if the use of the results informs management decisions that improve the net health outcome of care. The net health outcome can be improved if patients receive correct therapy, more effective therapy, or avoid unnecessary therapy or testing.

Review of Evidence
Direct Evidence

Direct evidence of clinical utility is provided by studies that have compared health outcomes for patients managed with and without the test. Because these are intervention studies, the preferred evidence would be from RCTs.

No RCTs were identified that support the clinical utility of vertebral motion analysis in this population.

Chain of Evidence
Indirect evidence on clinical utility rests on clinical validity. If the evidence is insufficient to demonstrate test performance, no inferences can be made about clinical utility.

Because the clinical validity of vertebral motion analysis has not been established for this indication, a chain of evidence cannot be constructed.

Section Summary: Vertebral Motion Analysis
Three studies with overlapping authors have been identified on vertebral motion analysis. These studies have reported that vertebral motion analysis reduces variability in the measurement of rotational and translational spine movement compared with standard flexion/extension radiographs. One study reported an improvement in diagnostic accuracy compared with flexion/extension radiographs, but the interpretation of this study is limited by the lack of a true reference standard.

Summary of Evidence
For individuals who have neck or back pain who receive dynamic spinal visualization, the evidence includes comparative trials. Relevant outcomes are test accuracy, symptoms, and functional outcomes. Techniques include digital motion X-rays, cineradiography/videofluoroscopy, or dynamic MRI of the spine and neck. Most available studies compare spine kinetics in patients who had neck or back pain with spine kinetics in healthy controls. In a feasibility study of 21 patients examining dynamic MRI for the detection of spondylolithesis, 3 dynamic MRI protocols demonstrated sensitivities of 68.8% to 78.6% when compared to standard flexion-extension radiographs. No evidence was identified on the effect of this technology on symptoms or functional outcomes. The evidence is insufficient to determine that the technology results in an improvement in the net health outcome.

For individuals who have back or neck pain who receive vertebral motion analysis, the evidence includes comparisons to standard flexion/extension radiographs. Relevant outcomes are test accuracy, symptoms, and functional outcomes. These studies reported that vertebral motion analysis reduces variability in measurement of rotational and translational spine movement compared with standard flexion/extension radiographs. Whether the reduction in variability improves diagnostic accuracy or health outcomes is uncertain. The single study that reported on diagnostic accuracy lacked a true criterion standard, limiting interpretation of findings. The evidence is insufficient to determine that the technology results in an improvement in the net health outcome.

The purpose of the following information is to provide reference material. Inclusion does not imply endorsement or alignment with the evidence review conclusions.

Practice Guidelines and Position Statements
Guidelines or position statements will be considered for inclusion in Supplemental Information if they were issued by, or jointly by, a U.S. professional society, an international society with U.S. representation, or National Institute for Health and Care Excellence (NICE). Priority will be given to guidelines that are informed by a systematic review, include strength of evidence ratings, and include a description of management of conflict of interest.

No guidelines or statements were identified.

U.S. Preventive Services Task Force Recommendations
Not applicable

Ongoing and Unpublished Clinical Trials
A search of ClinicalTrials.gov in August 2023 did not identify any ongoing or unpublished trials that would likely influence this review.

References: 

  1. Xu N, Wang S, Yuan H, et al. Does Dynamic Supine Magnetic Resonance Imaging Improve the Diagnostic Accuracy of Cervical Spondylotic Myelopathy? A Review of the Current Evidence. World Neurosurg. Apr 2017; 100: 474-479. PMID 28130164
  2. Teyhen DS, Flynn TW, Childs JD, et al. Arthrokinematics in a subgroup of patients likely to benefit from a lumbar stabilization exercise program. Phys Ther. Mar 2007; 87(3): 313-25. PMID 17311885
  3. Ahmadi A, Maroufi N, Behtash H, et al. Kinematic analysis of dynamic lumbar motion in patients with lumbar segmental instability using digital videofluoroscopy. Eur Spine J. Nov 2009; 18(11): 1677-85. PMID 19727854
  4. Walter WR, Alizai H, Bruno M, et al. Real-time dynamic 3-T MRI assessment of spine kinematics: a feasibility study utilizing three different fast pulse sequences. Acta Radiol. Jan 2021; 62(1): 58-66. PMID 32233646
  5. Hino H, Abumi K, Kanayama M, et al. Dynamic motion analysis of normal and unstable cervical spines using cineradiography. An in vivo study. Spine (Phila Pa 1976). Jan 15 1999; 24(2): 163-8. PMID 9926388
  6. Takayanagi K, Takahashi K, Yamagata M, et al. Using cineradiography for continuous dynamic-motion analysis of the lumbar spine. Spine (Phila Pa 1976). Sep 01 2001; 26(17): 1858-65. PMID 11568694
  7. Wong KW, Leong JC, Chan MK, et al. The flexion-extension profile of lumbar spine in 100 healthy volunteers. Spine (Phila Pa 1976). Aug 01 2004; 29(15): 1636-41. PMID 15284509
  8. Cheng B, Castellvi AE, Davis RJ, et al. Variability in Flexion Extension Radiographs of the Lumbar Spine: A Comparison of Uncontrolled and Controlled Bending. Int J Spine Surg. 2016; 10: 20. PMID 27441178
  9. Yeager MS, Cook DJ, Cheng BC. Reliability of computer-assisted lumbar intervertebral measurements using a novel vertebral motion analysis system. Spine J. Feb 01 2014; 14(2): 274-81. PMID 24239805
  10. Davis RJ, Lee DC, Wade C, et al. Measurement Performance of a Computer Assisted Vertebral Motion Analysis System. Int J Spine Surg. 2015; 9: 36. PMID 26273554

Coding Section  

Codes Number Description
CPT 76120 Cineradiography/videoradiography, except where specifically included
  76125 Cineradiography/videoradiography to complement routine examination (list separately in addition to code for primary procedure)
  76496 Unlisted fluoroscopic procedure (e.g., diagnostic, interventional)
  76499 Unlisted diagnostic radiographic procedure
  0743T

Bone Strength and fracture risk using finite element analysis of functional data and bone mineral density (BMD), with concurrent vertebral fracture assessment, utilizing data from a computed tomography scan, retrieval and transmission of the scan data, measurement of bone strength and BMD and classification of any vertebral fractures, with overall fracture-risk assessment, interpretation and report                                                                      

HCPCS    
ICD-10-CM   Investigational for all relevant diagnoses
  M54.2 Cervicalgia
  M54.50 Low back pain, unspecified (New code eff 10/01/2021)
  M54.51 Vertebrogenic low back pain (New code eff 10/01/2021)
  M54.59 Other low back pain (New code eff 10/01/2021)
ICD-10-PCS   ICD-10-PCS codes are only used for inpatient services.
  BR10ZZZ, BR17ZZZ, BR19ZZZ, BR1GZZZ Imaging, axial skeleton, fluoroscopy, codes for cervical, thoracic, lumbar and whole spine
Type of service  Radiology   
Place of service  Outpatient/inpatient   

Procedure and diagnosis codes on Medical Policy documents are included only as a general reference tool for each policy. They may not be all-inclusive.

This medical policy was developed through consideration of peer-reviewed medical literature generally recognized by the relevant medical community, U.S. FDA approval status, nationally accepted standards of medical practice and accepted standards of medical practice in this community, Blue Cross Blue Shield Association technology assessment program (TEC) and other nonaffiliated technology evaluation centers, reference to federal regulations, other plan medical policies and accredited national guidelines.

"Current Procedural Terminology © American Medical Association. All Rights Reserved" 

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